NBGN-100130 NebuChem™ Endotoxin Removal Resin.pdf

Size

1ml;5ml;Bulk

Description

NebuChem™ Endotoxin Removal Resin(CAT#NBGN-100130) utilizes immobilized polymixin B to bind and remove pyrogens from solution. The polymixins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymixin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide. Substances tested that do not interfere with performance includes: 20% DMSO, 20% ethanol, 20% glycerol; 1 M urea, 300 mM imidazole; 0.05% Tween 20, 10 mM DTT, etc.

Binding Capacity

Up to 2,000,000 EU/ml resin.

Ligand

Modified PMB (Polymixin B)

pH Stability

pH 5 -10

Support Matrix

4% cross-linked agarose, spherical beads

Mean Particle Size

90μm

Types of Sample

Protein, including peptides and antibody, polysaccharide, etc.

Applicable Ionic Strength

0.1 to 0.5 M NaCl

Storage

2 - 8°C; Freezing is prohibited